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AIM2 anticorps (AA 1-343)

AIM2 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
N° du produit ABIN522906
  • Antigène Voir toutes AIM2 Anticorps
    AIM2 (Absent in Melanoma 2 (AIM2))
    Épitope
    • 16
    • 10
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-343
    Reactivité
    • 68
    • 24
    • 18
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 56
    • 11
    • 2
    Souris
    Clonalité
    • 60
    • 9
    Polyclonal
    Conjugué
    • 38
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AIM2 est non-conjugé
    Application
    • 62
    • 34
    • 33
    • 21
    • 13
    • 13
    • 13
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Fonction
    Mouse polyclonal antibody raised against a full-length human AIM2 protein.
    Séquence
    MESKYKEILL LTGLDNITDE ELDRFKFFLS DEFNIATGKL HTANRIQVAT LMIQNAGAVS AVMKTIRIFQ KLNYMLLAKR LQEEKEKVDK QYKSVTKPKP LSQAEMSPAA SAAIRNDVAK QRAAPKVSPH VKPEQKQMVA QQESIREGFQ KRCLPVMVLK AKKPFTFETQ EGKQEMFHAT VATEKEFFFV KVFNTLLKDK FIPKRIIIIA RYYRHSGFLE VNSASRVLDA ESDQKVNVPL NIIRKAGETP KINTLQTQPL GTIVNGLFVV QKVTEKKKNI LFDLSDNTGK MEVLGVRNED TMKCKEGDKV RLTFFTLSKN GEKLQLTSGV HSTIKVIKAK KKT
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody reactive against mammalian transfected lysate.
    Immunogène
    AIM2 (NP_004824, 1 a.a. ~ 343 a.a) full-length human protein.
    Top Product
    Discover our top product AIM2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ansari, Singh, Dutta, Veettil, Dutta, Chikoti, Lu, Everly, Chandran: "Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells." dans: Journal of virology, Vol. 87, Issue 15, pp. 8606-23, (2013) (PubMed).

    Lee, Li, Gretz, Gebert, Dihlmann: "Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers." dans: Oncogene, Vol. 31, Issue 10, pp. 1242-53, (2012) (PubMed).

    Wang, Hsu, Chen, Liang, Chen, Ojcius, Tsang, Hsueh, Wu, Chang: "Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes." dans: Molecular & cellular proteomics : MCP, Vol. 11, Issue 11, pp. 1230-44, (2012) (PubMed).

    Fernandes-Alnemri, Yu, Datta, Wu, Alnemri: "AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA." dans: Nature, Vol. 458, Issue 7237, pp. 509-13, (2009) (PubMed).

  • Antigène
    AIM2 (Absent in Melanoma 2 (AIM2))
    Autre désignation
    AIM2 (AIM2 Produits)
    Synonymes
    anticorps AIM2, anticorps PYHIN4, anticorps Gm1313, anticorps Ifi210, anticorps absent in melanoma 2, anticorps AIM2, anticorps Aim2
    Sujet
    Full Gene Name: absent in melanoma 2
    Synonyms: PYHIN4
    ID gène
    9447
    NCBI Accession
    NM_004833
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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