GADD45GIP1 anticorps (N-Term)

N° du produit ABIN5536672

Détail du produit anti-GADD45GIP1 anticorps

Antigène: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Épitope: AA 13-45, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45GIP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GADD45GIP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 13-45 amino acids from the N-terminal region of human GADD45GIP1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For FACS starting dilution is: 1:25

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GADD45GIP1

Antigène: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Autre désignation: GADD45GIP1 (GADD45GIP1 Produits)

Synonymes: anticorps si:dkey-194e13.6, anticorps CKBBP2, anticorps CRIF1, anticorps PLINP, anticorps PLINP-1, anticorps PRG6, anticorps Plinp1, anticorps 2310040G17Rik, anticorps AI425883, anticorps Crif1, anticorps growth arrest and DNA-damage-inducible, gamma interacting protein 1, anticorps GADD45G interacting protein 1, anticorps gadd45gip1, anticorps GADD45GIP1, anticorps Gadd45gip1

Sujet: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Poids moléculaire: 25 kDa

ID gène: 90480

UniProt: Q8TAE8