TRPC6 anticorps (C-Term)

N° du produit ABIN400824

Détail du produit anti-TRPC6 anticorps

Antigène: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Épitope: C-Term

Reactivité: Humain, Chimpanzé

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRPC6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody is specific for Human TRPC6 protein.

Réactivité croisée (Details): Species reactivity (expected):Chimpanzee.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: TRP-6, Short transient receptor potential channel 6

Purification: Affinity Chromatography on Protein A

Immunogène: Synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6protein.

Clone: 3F2-H10-F2

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry: 2.5 μg/mL. Western Blot: 1/500- 1/2000. ELISA: 1/10000 - 1/50000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TRPC6

Antigène: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Autre désignation: TRPC6 (TRPC6 Produits)

Synonymes: anticorps FSGS2, anticorps TRP6, anticorps AV025995, anticorps LLHWJM002, anticorps LLHWJM003, anticorps LLHWJM004, anticorps TRP-6, anticorps Trrp6, anticorps mtrp6, anticorps trp6, anticorps bZ1P14.9, anticorps si:rp71-1p14.9, anticorps trpc6, anticorps transient receptor potential cation channel subfamily C member 6, anticorps transient receptor potential cation channel, subfamily C, member 6, anticorps transient receptor potential cation channel, subfamily C, member 6a, anticorps TRPC6, anticorps Trpc6, anticorps trpc6a, anticorps trpc6

Sujet: TRPC6, also known as TRP6, short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6, is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or Gprotein coupled receptors. It is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C and may not to be activated by intracellular calcium store depletion. Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS). Expression of this protein has been reported in tissues such as placenta, lung, spleen, ovary, small intestine, and renal podocytes. Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons, breast, respiratory, squamous and prostate epithelium, epidermis, placental trophoblasts, dendritic cells, and subsets of immune cells, and faint to moderate staining of adrenal, colon, ganglion cells, hepatocytes, heart, and testis.Synonyms: Short transient receptor potential channel 6, TRP-6, Transient receptor protein 6

ID gène: 7225

UniProt: Q9Y210