LGI3 anticorps (Center)
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- Antigène Voir toutes LGI3 Anticorps
- LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))
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Épitope
- Center
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LGI3 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects LGI3 at center. It will recognize both isoforms. The antibody is predicted to be specific to LGI3 and not recognize other LGI proteins. The observed higher molecular weight band may represent a post-translationally modified form of LGI3.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Peptide affinity chromatography
- Immunogène
- LGI3 antibody was raised against a 12 amino acid peptide from near the center of human LGI3.
- Isotype
- IgG
- Top Product
- Discover our top product LGI3 Anticorps primaire
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- Indications d'application
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))
- Autre désignation
- LGI3 (LGI3 Produits)
- Synonymes
- anticorps si:ch211-198o12.2, anticorps LGIL4, anticorps AI841179, anticorps AW049851, anticorps leucine rich repeat LGI family member 3, anticorps leucine-rich repeat LGI family, member 3, anticorps LGI3, anticorps lgi3, anticorps Lgi3
- Sujet
- The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Ab) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Ab. Two isoforms of LGI3 are known to exist.Synonyms: LGI1-like protein 4, LGI3, LGIL4, Leucine-rich glioma-inactivated protein 3, Leucine-rich repeat LGI family member 3
- ID gène
- 203190
- UniProt
- Q8N145
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