Recombinant Rab6-GTP (Gln72Leu-Mutant) anticorps (Atto 488)
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- Antigène
- Rab6-GTP
- Type d'anticorp
- Recombinant Antibody
- Épitope
- Gln72Leu-Mutant
- Reactivité
- Drosophila melanogaster, Humain, Souris
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Hôte
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Human
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Clonalité
- Monoclonal
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Conjugué
- Atto 488
- Application
- Immunocytochemistry (ICC)
- Specificité
- Recognizes human, mouse and Drosophila GTP-bound Rab6a and Rab6b and mutant Rab6Q72L.
- Réactivité croisée
- Mouche des fruits (Drosophila melanogaster), Humain, Souris
- Réactivité croisée (Details)
- Does not detect Rab6•GDP.
- Pureté
- >95 % (SDS-PAGE)
- Immunogène
- Recombinant Rab6AQ72L, a GTP-locked mutant of Rab6A in which Gln72 is replaced by Leu.
- Clone
- AA2
- Isotype
- IgG2
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- Commentaires
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anti-Rab6-GTP, monoclonal antibody (recombinant) (AA2) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain. anti-Rab6-GTP, monoclonal antibody (recombinant) (AA2) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C. - Date de péremption
- 12 months
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- Antigène
- Rab6-GTP
- Sujet
- Rab6 is involved in protein transport. It is a regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
- UniProt
- P20340
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