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PDHX anticorps (C-Term)

PDHX Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357414
  • Antigène Voir toutes PDHX Anticorps
    PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))
    Épitope
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 22
    • 19
    • 17
    Humain, Souris
    Hôte
    • 34
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 38
    • 1
    Polyclonal
    Conjugué
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDHX est non-conjugé
    Application
    • 30
    • 13
    • 13
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects PDX1 at C-term.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from selected from the C-terminal region of human PDX1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDHX Anticorps primaire
  • Indications d'application
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))
    Autre désignation
    PDHX / PDX1 (PDHX Produits)
    Synonymes
    anticorps DLDBP, anticorps E3BP, anticorps OPDX, anticorps PDX1, anticorps proX, anticorps AI481367, anticorps E3bp, anticorps Pdx1, anticorps Ac1164, anticorps zgc:66110, anticorps zgc:85977, anticorps MGC86218, anticorps PDHX, anticorps DDBDRAFT_0168431, anticorps DDBDRAFT_0230192, anticorps DDB_0168431, anticorps DDB_0230192, anticorps pyruvate dehydrogenase complex component X, anticorps pyruvate dehydrogenase complex, component X, anticorps pyruvate dehydrogenase complex component X L homeolog, anticorps E3-binding protein, anticorps PDHX, anticorps Pdhx, anticorps pdhx, anticorps pdhx.L, anticorps pdhX
    Sujet
    PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.Synonyms: Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein, E3BP, Lipoyl-containing pyruvate dehydrogenase complex component X, Pyruvate dehydrogenase protein X component mitochondrial, proX
    Poids moléculaire
    54122 Da
    ID gène
    8050, 9606
    UniProt
    O00330
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