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PDK2 anticorps (AA 187-276)

PDK2 Reactivité: Humain WB, ELISA, IHC (p), RNAi Hôte: Souris Monoclonal 2G1 unconjugated
N° du produit ABIN562160
  • Antigène Voir toutes PDK2 Anticorps
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    Épitope
    • 15
    • 15
    • 12
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 187-276
    Reactivité
    • 95
    • 54
    • 46
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 90
    • 12
    Souris
    Clonalité
    • 83
    • 19
    Monoclonal
    Conjugué
    • 44
    • 9
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PDK2 est non-conjugé
    Application
    • 86
    • 53
    • 44
    • 17
    • 14
    • 13
    • 9
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
    Fonction
    Mouse monoclonal antibody raised against a partial recombinant PDK2.
    Séquence
    HIGSIDPNCN VSEVVKDAYD MAKLLCDKYY MASPDLEIQE INAANSKQPI HMVYVPSHLY HMLFELFKNA MRATVESHES SLILPPIKVM
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    PDK2 (AAH05811, 187 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2G1
    Isotype
    IgG2a
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Gannon, Ables, Crawford, Lowe, Offield, Magnuson, Wright: "pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis." dans: Developmental biology, Vol. 314, Issue 2, pp. 406-17, (2008) (PubMed).

    Babu, Deering, Mirmira: "A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis." dans: Molecular genetics and metabolism, Vol. 92, Issue 1-2, pp. 43-55, (2007) (PubMed).

    Gu, Dubauskaite, Melton: "Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors." dans: Development (Cambridge, England), Vol. 129, Issue 10, pp. 2447-57, (2002) (PubMed).

    Ohlsson, Karlsson, Edlund: "IPF1, a homeodomain-containing transactivator of the insulin gene." dans: The EMBO journal, Vol. 12, Issue 11, pp. 4251-9, (1993) (PubMed).

  • Antigène
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    Autre désignation
    PDK2 (PDK2 Produits)
    Synonymes
    anticorps PDHK2, anticorps PDKII, anticorps Pdk, anticorps zgc:56209, anticorps PDK2, anticorps pyruvate dehydrogenase kinase 2, anticorps pyruvate dehydrogenase kinase, isoenzyme 2, anticorps pyruvate dehydrogenase kinase, isozyme 2b, anticorps PDK2, anticorps Pdk2, anticorps pdk2b
    Sujet
    Full Gene Name: pyruvate dehydrogenase kinase, isozyme 2
    Synonyms: PDHK2
    ID gène
    5164
    Pathways
    Signalisation PI3K-Akt, Signalisation RTK, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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