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CHFR anticorps (AA 1-652)

CHFR Reactivité: Humain ELISA, WB, IHC (p), RNAi Hôte: Souris Monoclonal 1H3-A12 unconjugated
N° du produit ABIN565913
  • Antigène Voir toutes CHFR Anticorps
    CHFR (Checkpoint with Forkhead and Ring Finger Domains (CHFR))
    Épitope
    • 8
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-652
    Reactivité
    • 44
    • 13
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 41
    • 2
    • 1
    Souris
    Clonalité
    • 42
    • 2
    Monoclonal
    Conjugué
    • 17
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CHFR est non-conjugé
    Application
    • 25
    • 23
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
    Fonction
    Mouse monoclonal antibody raised against a full length recombinant CHFR.
    Séquence
    MERPEEGKQS PPPQPWGRLL RLGAEEGEPH VLLRKREWTI GRRRGCDLSF PSNKLVSGDH CRIVVDEKSG QVTLEDTSTS GTVINKLKVV KKQTCPLQTG DVIYLVYRKN EPEHNVAYLY ESLSEKQGMT QESFDTSGAG AGRGADPRVP PSSPATQVCF EEPQPSTSTS DLFPTASASS TEPSPAGRER SSSCGSGGGG ISPKGSGPSV ASDEVSSFAS ALPDRKTASF SSLEPQDQED LEPVKKKMRG DGDLDLNGQL LVAQPRRNAQ TVHEDVRAAA GKPDKMEETL TCIICQDLLH DCVSLQPCMH TFCAACYSGW MERSSLCPTC RCPVERICKN HILNNLVEAY LIQHPDKSRS EEDVQSMDAR NKITQDMLQP KVRRSFSDEE GSSEDLLELS DVDSESSDIS QPYVVCRQCP EYRRQAAQPP HCPAPEGEPG APQALGDAPS TSVSLTTAVQ DYVCPLQGSH ALCTCCFQPM PDRRVEREQD PRVAPQQCAV CLQPFCHLYW GCTRTGCYGC LAPFCELNLG DKCLDGVLNN NSYESDILKN YLATRGLTWK NMLTESLVAL QRGVFLLSDY RVTGDTVLCY CCGLRSFREL TYQYRQNIPA SELPVAVTSR PDCYWGRNCR TQVKAHHAMK FNHICEQTRF KN
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    CHFR (AAH12072.1, 1 a.a. ~ 652 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1H3-A12
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Fujita, Yamamoto, Imamura, Nakamura, Maehara, Tsuneyoshi, Oda: "Expression level of the mitotic checkpoint protein and G2-M cell cycle regulators and prognosis in gastrointestinal stromal tumors in the stomach." dans: Virchows Archiv : an international journal of pathology, Vol. 460, Issue 2, pp. 163-9, (2012) (PubMed).

    Kashima, Idogawa, Mita, Shitashige, Yamada, Ogi, Suzuki, Toyota, Ariga, Sasaki, Tokino: "CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation." dans: The Journal of biological chemistry, Vol. 287, Issue 16, pp. 12975-84, (2012) (PubMed).

    Hu, Huang, Sun, Wu, Xu, Yin, Chen, Jiang, Shen: "Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer." dans: Medical oncology (Northwood, London, England), Vol. 28, Issue 2, pp. 447-54, (2011) (PubMed).

    Privette, Weier, Nguyen, Yu, Petty: "Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint." dans: Neoplasia (New York, N.Y.), Vol. 10, Issue 7, pp. 643-52, (2008) (PubMed).

    Gao, Xin, Zhang, Zhou: "Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma." dans: World journal of gastroenterology : WJG, Vol. 14, Issue 32, pp. 5000-7, (2008) (PubMed).

    Milne, Sitarz, Carvalho, Polak, Ligtenberg, Pauwels, Offerhaus, Weterman: "Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis." dans: Human pathology, Vol. 38, Issue 6, pp. 903-13, (2007) (PubMed).

    Privette, González, Ding, Kleer, Petty: "Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression." dans: Cancer research, Vol. 67, Issue 13, pp. 6064-74, (2007) (PubMed).

  • Antigène
    CHFR (Checkpoint with Forkhead and Ring Finger Domains (CHFR))
    Autre désignation
    CHFR (CHFR Produits)
    Synonymes
    anticorps RNF116, anticorps RNF196, anticorps CHFR, anticorps fc43f10, anticorps si:dkey-69h6.7, anticorps wu:fc43f10, anticorps rnf116, anticorps rnf196, anticorps 5730484M20Rik, anticorps C230082M18, anticorps checkpoint with forkhead and ring finger domains, anticorps checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase, anticorps checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase L homeolog, anticorps CHFR, anticorps chfr, anticorps Chfr, anticorps chfr.L
    Sujet
    Full Gene Name: checkpoint with forkhead and ring finger domains
    Synonyms: FLJ10796,FLJ33629,RNF116,RNF196
    ID gène
    55743
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