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IKBKG anticorps (AA 61-137)
IKBKG
Reactivité: Humain
WB
Hôte: Souris
Monoclonal
DA10-12
unconjugated
Détail du produit anti-IKBKG anticorps
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Antigène
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IKBKG
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
Épitope
Tous les épitopes à travers IKBKG Anticorps.
AA 61-137
Reactivité
Toutes les réactivités sur IKBKG Anticorps
Humain
Hôte
Toutes les hôtes sur IKBKG Anticorps
Souris
Clonalité
Toutes les clonalités sur IKBKG Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers IKBKG Anticorps
Cet anticorp IKBKG est non-conjugé
Application
Tous les applications à travers IKBKG Anticorps.
Western Blotting (WB)
Specificité
This antibody reacts with IKKG (45 kDa) on Western blotting.
Purification
Protein-A Agarose Chromatography of hybridoma supernatant.
Immunogène
Human recombinant GST-IKKG (a.a. 61-137).
Clone
DA10-12
Isotype
IgG1
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS, pH 7.2 containing 50 % Glycerol without preservatives.
Agent conservateur
Without preservative
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Store the antibody (in aliquots) at -20 °C.
Détails sur IKBKG
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Antigène
IKBKG
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
Autre désignation
NEMO / IKBKG (IKBKG Produits )
Synonymes
anticorps AMCBX1, anticorps FIP-3, anticorps FIP3, anticorps Fip3p, anticorps IKK-gamma, anticorps IP, anticorps IP1, anticorps IP2, anticorps IPD2, anticorps NEMO, anticorps ZC2HC9, anticorps 1110037D23Rik, anticorps AI848108, anticorps AI851264, anticorps AW124339, anticorps IKK[g], anticorps Nemo, anticorps nemo, anticorps fj33c07, anticorps wu:fj33c07, anticorps zgc:113492, anticorps MGC97885, anticorps IKBKG, anticorps IKBKG_1, anticorps IKBKG_2, anticorps CG16910, anticorps DmIKK-gamma, anticorps DmIKKgamma, anticorps Dmel\\CG16910, anticorps Dmikkgamma, anticorps IKK, anticorps IKK[[gamma]], anticorps IKKg, anticorps IKKgamma, anticorps KEY, anticorps Kenny, anticorps Key, anticorps dIKK, anticorps dIKK-gamma, anticorps dmIKKgamma, anticorps inhibitor of nuclear factor kappa B kinase subunit gamma, anticorps inhibitor of kappaB kinase gamma, anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, anticorps inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog, anticorps kenny, anticorps IKBKG, anticorps Ikbkg, anticorps ikbkg, anticorps ikbkg.L, anticorps IKBKG_1, anticorps key
Sujet
The I-kB kinase complex (IKK) functions as a mediator of NF-kB activation in response to multiple stimuli by phosphorylating I-kB inhibitor proteins and causing their degradation. IKK contains two structurally related catalytic subunits termed IKKA and IKKB as well as a noncatalytic subunit called IKKG/NEMO. IKK is composed of a IKKG/NEMO homodimer bound together with either an IKKA/IKKB heterodimer or an IKKB homodimer. Although IKKG /NEMO itself does not have kinase activity, it is essential for NF-kB activation likely via a scaffold function that is required for IKK activity. Mutations in the X-linked gene encoding IKKG can interfere with NF-kB signaling and lead to immunodeficiency disease.Synonyms: FIP-3, FIP3, I-kappa-B kinase subunit gamma, IKK-gamma, IKKAP1, IKKG, IkB kinase subunit gamma, IkB kinase-associated protein 1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, NF-kappa-B essential modifier, NF-kappa-B essential modulator
ID gène
8517
NCBI Accession
NP_001093326
UniProt
Q9Y6K9
Pathways
Signalisation NF-kappaB , Signalisation RTK , TCR Signaling , Signalisation TLR , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , M Phase , Production of Molecular Mediator of Immune Response , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
Vus récemment
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