MAD2L1 anticorps

N° du produit ABIN567786

Détail du produit anti-MAD2L1 anticorps

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAD2L1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificité: This antibody reacts with MAD2 (25 kDa) on Western blotting and Immunoprecipitation.

Purification: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogène: Recombinant Human MAD2.

Clone: 2G9

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur MAD2L1

Antigène: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Autre désignation: MAD2L1 (MAD2L1 Produits)

Synonymes: anticorps HSMAD2, anticorps MAD2, anticorps MXD2, anticorps MXI, anticorps bHLHc11, anticorps AA673185, anticorps cb408, anticorps zgc:112133, anticorps mad2, anticorps XMad2, anticorps MAD2L1, anticorps mitotic arrest deficient 2 like 1, anticorps MAX interactor 1, dimerization protein, anticorps MAD2 mitotic arrest deficient-like 1, anticorps MAD2 mitotic arrest deficient-like 1 (yeast), anticorps mitotic arrest deficient 2 like 1 S homeolog, anticorps MAD2L1, anticorps MXI1, anticorps Mad2l1, anticorps mad2l1, anticorps mad2l1.S

Sujet: Some of the spindle checkpoint components are evolutionarily conserved from yeast to human. They include mitotic arrest deficiency 1 (MAD1), MAD2, MAD3/BUBR1, budding uninhibited by benomyl 1 (BUB1), BUB3, and monopolar spindle 1 (MPS1). MAD1 interacts with several checkpoint proteins, forming a complex with MAD2 and recruiting MAD2 to unattached kinetochores. MAD1 and Cdc20 can bind MAD2, but these two bindings are exclusive. They share a 10-residue MAD2-binding motif. It has been suggested that MAD1 acts as a positive regulator and a competitive inhibitor of the MAD2-Cdc20 complex.Synonyms: MAD2, Mitotic spindle assembly checkpoint protein MAD2A

ID gène: 4085

NCBI Accession: NP_002349

UniProt: Q13257