RAD21 anticorps (C-Term)

N° du produit ABIN567792

Détail du produit anti-RAD21 anticorps

Antigène: RAD21 (RAD21 Homolog (RAD21))

Épitope: AA 544-631, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD21 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificité: This antibody reacts with Cohesin (120 kDa) on Western blotting.

Purification: Protein-A Agarose Chromatography of hybridoma supernatant.

Immunogène: Recombinant C-terminal fragment (544-631 aa) of Scc1 subunit of Human Cohesin (hRad21).

Clone: CM110-2C10

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur RAD21

Antigène: RAD21 (RAD21 Homolog (RAD21))

Autre désignation: RAD21 (RAD21 Produits)

Sujet: Cohesin in eukaryotic cells is mediated by a multisubunit protein complex. Cohesin consists of four proteins: Smc1, Smc3, Scc1/Mcd1/hRad21, which is called kleisin and is the target of the protease separase, and Scc3/Irr1. Cohesin holds sister chromatids together until they separate into daughter cells during mitosis and also prevents splitting of chromosomes once bipolar attachments are made.Synonyms: Double-strand-break repair protein rad21 homolog, HR21, KIAA0078, NXP1, Nuclear matrix protein 1, SCC1 homolog

ID gène: 5885

NCBI Accession: NP_006256

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity