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TRPC7 anticorps (Internal Region)

Verified TRPC7 Reactivité: Souris, Poulet WB, IP, ELISA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN570738
  • Antigène Voir toutes TRPC7 Anticorps
    TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))
    Épitope
    • 13
    • 11
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 44
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris, Poulet
    Hôte
    • 30
    • 15
    Chèvre
    Clonalité
    • 30
    • 15
    Polyclonal
    Conjugué
    • 18
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRPC7 est non-conjugé
    Application
    • 36
    • 17
    • 15
    • 14
    • 13
    • 13
    • 11
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), ELISA
    Fonction
    TRPC7
    Séquence
    KLCKSKAKSC END
    Specificité
    This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1, NP_001161049.1, NP_001161048.1).
     Réactivité croisée
    Boeuf (Vache), Chien, Humain, Souris, Rat
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Classe de qualité
    Verified
    Immunogène
    Peptide with sequence KLCKSKAKSCEND, from the internal region of the protein sequence according to NP_065122.1, NP_001161049.1, NP_001161048.1.
    Isotype
    IgG
    Top Product
    Discover our top product TRPC7 Anticorps primaire
  • Indications d'application

    Western Blot: A 95 kDa band was observed in Chicken Embryo Heart atrial and ventricular myocyte lysates (Sabourin et al, PMID 21672930). This antibody has been successfully used in WB on Mouse (Murtaza et al., PMID: 32882106).

    Peptide ELISA: antibody detection limit dilution 1:32000.

    Commentaires

    Immunoprecipitation: This antibody has been successfully used in IP on lysates of Chicken Embryo Heart (Sabourin et al, PMID: 21672930).

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Minimize freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Sabourin, Antigny, Robin, Frieden, Raddatz: "Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conduction." dans: The Journal of biological chemistry, Vol. 287, Issue 32, pp. 26688-701, (2012) (PubMed).

    Sabourin, Robin, Raddatz: "A key role of TRPC channels in the regulation of electromechanical activity of the developing heart." dans: Cardiovascular research, Vol. 92, Issue 2, pp. 226-36, (2011) (PubMed).

  • Antigène
    TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))
    Autre désignation
    TRPC7 (TRPC7 Produits)
    Synonymes
    anticorps TRP7, anticorps TRP-7, anticorps Trrp8, anticorps TRPC7, anticorps TRPM2, anticorps transient receptor potential cation channel subfamily C member 7, anticorps transient receptor potential cation channel, subfamily C, member 7, anticorps short transient receptor potential channel 7, anticorps TRPC7, anticorps Trpc7, anticorps LOC100012798
    Sujet
    TRPC7, transient receptor potential cation channel, subfamily C, member 7, TRP7, likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7, putative capacitative calcium channel
    ID gène
    57113, 26946, 282822
    NCBI Accession
    NP_065122, NP_001161049, NP_001161048
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