Souris anti-Humain IgG (Fc Region) Anticorps

Détails pour le produit réf. ABIN614786, Fournisseur: Connectez-vous pour afficher
Antigène
Épitope
Fc Region
4681
2537
1878
1066
1006
860
298
294
35
34
31
8
7
7
3
3
2
2
1
1
1
1
1
Reactivité
Humain
2849
2735
2296
1675
1433
788
613
442
380
379
358
339
291
290
208
138
135
122
41
29
27
25
12
11
9
8
6
5
5
5
4
4
4
4
4
4
4
4
3
3
3
2
2
1
1
1
1
1
Hôte
Souris
6705
4831
1795
890
609
388
91
55
52
21
8
5
5
5
2
1
1
Clonalité (Clone)
Monoclonal ()
Application
Immunofluorescence (IF)
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Immunogène Fusion protein of human IgG Fc fragment
Clone EM-07
Isotype IgG1
Réactivité croisée (Details) Species reactivity (tested):Human.
Purification Protein A affinity Chromatography
Pureté > 95 % pure by SDS-PAGE
Sujet Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75 % of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.Synonyms: Human Immunoglobulin G
Poids moléculaire 150 kDa
Domaine de recherche Immunology, Secondary Antibodies
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, pH ~7.4, 15 mM Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for Mouse anti-Human IgG (Fc Region) antibody (ABIN614786) Mouse anti-Human IgG (Fc Region) antibody
Background publications Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." dans: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." dans: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." dans: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).

Franklin: "Structure and function of immunoglobulins." dans: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).