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CD72 anticorps (PE)

CD72 Reactivité: Humain FACS Hôte: Souris Monoclonal 3F3 PE
N° du produit ABIN616763
  • Antigène Voir toutes CD72 Anticorps
    CD72 (CD72 Molecule (CD72))
    Reactivité
    • 47
    • 19
    • 1
    Humain
    Hôte
    • 37
    • 21
    • 1
    Souris
    Clonalité
    • 37
    • 22
    Monoclonal
    Conjugué
    • 26
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD72 est conjugé à/à la PE
    Application
    • 29
    • 24
    • 23
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody reacts with CD72, a 39-43 kDa type II membrane glycoprotein (C-type lectin family). CD72 is a pan-B cell marker expressed throughout the B lymphocytes diferentiation with the exception of plasma cells, it is also present on follicular dendritic cells.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Immunogène
    Normal human lymphocytes from a lymph node
    Clone
    3F3
    Isotype
    IgG2b
    Top Product
    Discover our top product CD72 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Dilute only prior to immediate use
    Stock
    4 °C
    Stockage commentaire
    Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
  • Antigène
    CD72 (CD72 Molecule (CD72))
    Autre désignation
    CD72 (CD72 Produits)
    Synonymes
    anticorps CD72c, anticorps Ly-19, anticorps Ly-32, anticorps Ly-m19, anticorps Lyb-2, anticorps CD72b, anticorps LYB2, anticorps CD72 antigen, anticorps CD72 molecule, anticorps Cd72, anticorps CD72
    Sujet
    CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.Synonyms: B-Cell marker, B-cell differentiation antigen CD72, Ly-32, Ly32, Lyb-2, Lymphocyte antigen 32
    ID gène
    971
    NCBI Accession
    NP_001773
    UniProt
    P21854
    Pathways
    BCR Signaling
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