VEGFC anticorps

N° du produit ABIN650694

Détail du produit anti-VEGFC anticorps

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEGFC est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This VEGFC antibody is generated from rabbits immunized with VEGFC recombinant protein.

Clone: RB22679

Isotype: IgG

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-VEGFC (ABIN650694)

Dai, Liu, Liu, Zhang, Wang, Jin, Qian, Wang, Zhao, Wu, Xiong, Chang, Sun, Yang, Hoffman, Liu: "Anti-metastatic Efficacy of Traditional Chinese Medicine (TCM) Ginsenoside Conjugated to a VEFGR-3 Antibody on Human Gastric Cancer in an Orthotopic Mouse Model." dans: Anticancer research, Vol. 37, Issue 3, pp. 979-986, (2017) (PubMed).

Zhao, Hou, Hou, Zhu: "Concurrent Expression of VEGF-C and Neuropilin-2 Is Correlated with Poor Prognosis in Glioblastoma." dans: The Tohoku journal of experimental medicine, Vol. 238, Issue 2, pp. 85-91, (2016) (PubMed).

Yang, Wang, Dong, Shen, Guo, Liu, Liu, Zhang, Li, Sun: "Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways." dans: American journal of cancer research, Vol. 5, Issue 10, pp. 3085-97, (2015) (PubMed).

Shi, Yang, Shen, Yang, Xu, Qiu, Sun, Zhang, Wang, Zhu, Qin, Tang, Fan, Zhou: "High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery." dans: Cancer, Vol. 119, Issue 5, pp. 993-1003, (2013) (PubMed).

Hirata, Hinoda, Ueno, Shahryari, Tabatabai, Dahiya: "MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer." dans: Carcinogenesis, Vol. 33, Issue 1, pp. 41-8, (2011) (PubMed).

Détails sur VEGFC

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Autre désignation: VEGFC (VEGFC Produits)

Sujet: VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Poids moléculaire: 46883

ID gène: 7424

NCBI Accession: NP_005420

UniProt: P49767

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2