Caspase 3 anticorps (Cleaved-Asp175)
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- Antigène Voir toutes Caspase 3 (CASP3) Anticorps
- Caspase 3 (CASP3)
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Épitope
- AA 149-175, Cleaved-Asp175
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Caspase 3 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)
- Homologie
- B, M, Pig, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This Cleaved antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-175 amino acids from human Cleaved.
- Clone
- RB25833
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CASP3 Anticorps primaire
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- Indications d'application
- IHC-P: 1:50~100. DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1." dans: Scientific reports, Vol. 6, pp. 32189, (2018) (PubMed).
: "Functional Characterization of Long Noncoding RNA Lnc_bc060912 in Human Lung Carcinoma Cells." dans: Biochemistry, Vol. 54, Issue 18, pp. 2895-902, (2015) (PubMed).
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The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1." dans: Scientific reports, Vol. 6, pp. 32189, (2018) (PubMed).
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- Antigène
- Caspase 3 (CASP3)
- Autre désignation
- CASP3 (CASP3 Produits)
- Synonymes
- anticorps CPP32, anticorps CPP32B, anticorps SCA-1, anticorps A830040C14Rik, anticorps AC-3, anticorps Apopain, anticorps CC3, anticorps Caspase-3, anticorps Lice, anticorps Yama, anticorps mldy, anticorps xcpp32, anticorps casp3, anticorps zgc:100890, anticorps CASP-3, anticorps caspase-3, anticorps caspase 3, anticorps caspase 3 S homeolog, anticorps caspase 3, apoptosis-related cysteine peptidase a, anticorps caspase 3, apoptosis-related cysteine peptidase, anticorps CASP3, anticorps Casp3, anticorps casp3.S, anticorps casp3a
- Sujet
- CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
- Poids moléculaire
- 31608
- ID gène
- 836
- NCBI Accession
- NP_004337, NP_116786
- UniProt
- P42574
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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