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Caspase 3 anticorps (Asp175)

CASP3 Reactivité: Humain, Rat WB, IHC (p), FACS Hôte: Lapin Polyclonal RB25834 unconjugated
N° du produit ABIN651176
  • Antigène Voir toutes Caspase 3 (CASP3) Anticorps
    Caspase 3 (CASP3)
    Épitope
    • 19
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 11
    • 10
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 149-179, Asp175
    Reactivité
    • 281
    • 196
    • 148
    • 31
    • 17
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 281
    • 42
    • 4
    • 2
    • 2
    Lapin
    Clonalité
    • 273
    • 57
    Polyclonal
    Conjugué
    • 161
    • 27
    • 21
    • 14
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    Cet anticorp Caspase 3 est non-conjugé
    Application
    • 254
    • 109
    • 105
    • 84
    • 79
    • 65
    • 51
    • 37
    • 34
    • 29
    • 28
    • 20
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This CASP3(Asp175) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-179 amino acids from human CASP3(Asp175).
    Clone
    RB25834
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CASP3 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000-1:2000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    Caspase 3 (CASP3)
    Autre désignation
    CASP3 (CASP3 Produits)
    Synonymes
    anticorps CPP32, anticorps CPP32B, anticorps SCA-1, anticorps A830040C14Rik, anticorps AC-3, anticorps Apopain, anticorps CC3, anticorps Caspase-3, anticorps Lice, anticorps Yama, anticorps mldy, anticorps xcpp32, anticorps casp3, anticorps zgc:100890, anticorps CASP-3, anticorps caspase-3, anticorps caspase 3, anticorps caspase 3 S homeolog, anticorps caspase 3, apoptosis-related cysteine peptidase a, anticorps caspase 3, apoptosis-related cysteine peptidase, anticorps CASP3, anticorps Casp3, anticorps casp3.S, anticorps casp3a
    Sujet
    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
    Poids moléculaire
    31608
    ID gène
    836
    NCBI Accession
    NP_004337, NP_116786
    UniProt
    P42574
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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