ABCD1 anticorps (AA 257-285)

N° du produit ABIN654412

Détail du produit anti-ABCD1 anticorps

Antigène: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Épitope: AA 257-285

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCD1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ABCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human ABCD1.

Clone: RB18846

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ABCD1

Antigène: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Autre désignation: ABCD1 (ABCD1 Produits)

Synonymes: anticorps ABC42, anticorps ALD, anticorps ALDP, anticorps AMN, anticorps RGD1562128, anticorps zgc:172102, anticorps ABCD1, anticorps Ald, anticorps Aldgh, anticorps ATP binding cassette subfamily D member 1, anticorps ATP-binding cassette, sub-family D (ALD), member 1, anticorps ATP-binding cassette sub-family D member 1, anticorps ATP binding cassette subfamily D member 1 L homeolog, anticorps ABCD1, anticorps Abcd1, anticorps abcd1, anticorps CpipJ_CPIJ013253, anticorps VDBG_05717, anticorps abcd1.L

Sujet: ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Poids moléculaire: 82937

ID gène: 215

NCBI Accession: NP_000024

UniProt: P33897

Pathways: Monocarboxylic Acid Catabolic Process