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JNK anticorps (AA 159-195)

MAPK8 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB28968 unconjugated
N° du produit ABIN654887
  • Antigène Voir toutes JNK (MAPK8) Anticorps
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    Épitope
    • 61
    • 28
    • 17
    • 16
    • 16
    • 10
    • 9
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 159-195
    Reactivité
    • 213
    • 118
    • 101
    • 43
    • 34
    • 20
    • 18
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 195
    • 23
    • 3
    Lapin
    Clonalité
    • 179
    • 42
    Polyclonal
    Conjugué
    • 104
    • 18
    • 16
    • 14
    • 12
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp JNK est non-conjugé
    Application
    • 166
    • 93
    • 57
    • 43
    • 40
    • 39
    • 37
    • 30
    • 21
    • 18
    • 14
    • 12
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M, Rat, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This MAPK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-195 amino acids from human MAPK8.
    Clone
    RB28968
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAPK8 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
    Autre désignation
    MAPK8 (MAPK8 Produits)
    Synonymes
    anticorps JNK, anticorps JNK-46, anticorps JNK1, anticorps JNK1A2, anticorps JNK21B1/2, anticorps PRKM8, anticorps SAPK1, anticorps SAPK1c, anticorps AI849689, anticorps Prkm8, anticorps BSK, anticorps BSK/DJNK, anticorps Bsk, anticorps CG5680, anticorps D-JNK, anticorps D-junk, anticorps DBSK/JNK, anticorps DJNK, anticorps DJNK/bsk, anticorps Dmel\\CG5680, anticorps JNK/SAPK, anticorps Jnk, anticorps Junk, anticorps SAPKa, anticorps c-Jun, anticorps dJNK, anticorps jnk, anticorps T10F20.15, anticorps jnk1, anticorps sapk1, anticorps mapk8, anticorps zgc:112379, anticorps JNKb, anticorps mapk8b, anticorps mitogen-activated protein kinase 8, anticorps Stress-activated protein kinase jnk-1, anticorps basket, anticorps Protein kinase superfamily protein, anticorps mitogen-activated protein kinase 8 L homeolog, anticorps mitogen-activated protein kinase 8b, anticorps mitogen-activated protein kinase 8B-like, anticorps MAPK8, anticorps jnk-1, anticorps Mapk8, anticorps bsk, anticorps ATMPK8, anticorps mapk8.L, anticorps mapk8b, anticorps LOC109094263
    Sujet
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Poids moléculaire
    48296
    ID gène
    5599
    NCBI Accession
    NP_001265476, NP_002741, NP_620634, NP_620637
    UniProt
    P45983
    Pathways
    Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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