RECQL2 anticorps (AA 787-816)

N° du produit ABIN656017

Détail du produit anti-RECQL2 anticorps

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Épitope: AA 787-816

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RECQL2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This WRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 787-816 amino acids from the Central region of human WRN.

Clone: RB17383

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-RECQL2 (ABIN656017)

Kawakubo-Yasukochi, Morioka, Hazekawa, Yasukochi, Nishinakagawa, Ono, Kawano, Nakamura, Nakashima: "miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment." dans: Molecular carcinogenesis, Vol. 57, Issue 2, pp. 295-302, (2018) (PubMed).

Détails sur RECQL2

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Autre désignation: WRN (WRN Produits)

Synonymes: anticorps RECQ3, anticorps RECQL2, anticorps RECQL3, anticorps xBLM, anticorps recq2, anticorps recql2, anticorps recql3, anticorps AI846146, anticorps ffa-1, anticorps xwrn, anticorps RGD1564788, anticorps Werner syndrome RecQ like helicase, anticorps mediator of RNA polymerase II transcription subunit 34, anticorps Bloom syndrome RecQ like helicase, anticorps Werner syndrome, RecQ helicase-like L homeolog, anticorps WRN, anticorps LOC9327212, anticorps blm, anticorps Wrn, anticorps wrn.L

Sujet: This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.

Poids moléculaire: 162461

ID gène: 7486

NCBI Accession: NP_000544

UniProt: Q14191

Pathways: Réparation de l'ADN