SHANK2 anticorps (AA 879-908)

N° du produit ABIN656710

Détail du produit anti-SHANK2 anticorps

Antigène: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Épitope: AA 879-908

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHANK2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SHANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2.

Clone: RB31120

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SHANK2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-SHANK2 (ABIN656710)

de Sena Cortabitarte, Berkel, Cristian, Fischer, Rappold: "A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders." dans: Journal of neurodevelopmental disorders, Vol. 10, Issue 1, pp. 15, (2018) (PubMed).

Détails sur SHANK2

Antigène: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Autre désignation: SHANK2 (SHANK2 Produits)

Synonymes: anticorps AUTS17, anticorps CORTBP1, anticorps CTTNBP1, anticorps ProSAP1, anticorps SHANK, anticorps SPANK-3, anticorps mKIAA1022, anticorps auts17, anticorps cortbp1, anticorps cttnbp1, anticorps prosap1, anticorps spank-3, anticorps shank2, anticorps MGC122482, anticorps CortBP1, anticorps Spank-3, anticorps SHANK2, anticorps SH3 and multiple ankyrin repeat domains 2, anticorps SH3 and multiple ankyrin repeat domains 2 L homeolog, anticorps SH3 and multiple ankyrin repeat domains protein 2, anticorps SHANK2, anticorps Shank2, anticorps shank2.L, anticorps shank2, anticorps LOC100438523

Sujet: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq].

Poids moléculaire: 158822

ID gène: 22941

NCBI Accession: NP_036441

UniProt: Q9UPX8