C10orf2 anticorps (C-Term)

N° du produit ABIN656726

Détail du produit anti-C10orf2 anticorps

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Épitope: AA 656-684, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C10orf2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This C10orf2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-684 amino acids from the C-terminal region of human C10orf2.

Clone: RB32016

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: C10orf2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur C10orf2

Antigène: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Autre désignation: C10orf2 (C10ORF2 Produits)

Synonymes: anticorps ATXN8, anticorps IOSCA, anticorps MTDPS7, anticorps PEO, anticorps PEO1, anticorps PEOA3, anticorps SANDO, anticorps SCA8, anticorps TWINL, anticorps C6H10orf2, anticorps D19Ertd626e, anticorps Twinl, anticorps twinkle mtDNA helicase L homeolog, anticorps twinkle mtDNA helicase, anticorps twnk.L, anticorps TWNK, anticorps Twnk

Sujet: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 77154

ID gène: 56652

NCBI Accession: NP_001157284, NP_068602

UniProt: Q96RR1