PACS2 anticorps (C-Term)

N° du produit ABIN657066

Détail du produit anti-PACS2 anticorps

Antigène: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Épitope: AA 642-671, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PACS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PACS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 642-671 amino acids from the C-terminal region of human PACS2.

Clone: RB32549

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PACS2

Antigène: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Autre désignation: PACS2 (PACS2 Produits)

Synonymes: anticorps PACS-2, anticorps PACS1L, anticorps 6720425G15Rik, anticorps AW208651, anticorps AW489976, anticorps E230011J22, anticorps Pacs1l, anticorps mKIAA0602, anticorps phosphofurin acidic cluster sorting protein 2, anticorps PACS2, anticorps Pacs2

Sujet: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Poids moléculaire: 97702

NCBI Accession: NP_001094383, NP_001230056, NP_056012

UniProt: Q86VP3