NFATC1 anticorps (C-Term)

N° du produit ABIN657821

Détail du produit anti-NFATC1 anticorps

Antigène: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Épitope: AA 898-927, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFATC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 amino acids from the C-terminal region of human NFATC1.

Clone: RB34041

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: NFATC1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur NFATC1

Antigène: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Autre désignation: NFATC1 (NFATC1 Produits)

Synonymes: anticorps nf-atc, anticorps nfat2, anticorps nfatc, anticorps si:ch211-198c22.2, anticorps NFATC1, anticorps 2210017P03Rik, anticorps AI449492, anticorps AV076380, anticorps NF-ATc, anticorps NFAT2, anticorps NFATc, anticorps Nfatcb, anticorps NF-ATC, anticorps NF-ATc1, anticorps NFAT, anticorps NFATmac, anticorps nuclear factor of activated T-cells 1, anticorps nuclear factor of activated T-cells 1 L homeolog, anticorps nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, anticorps NFATC1, anticorps nfatc1.L, anticorps nfatc1, anticorps Nfatc1

Sujet: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Poids moléculaire: 101243

ID gène: 4772

NCBI Accession: NP_001265598, NP_001265599, NP_001265601, NP_001265602, NP_001265604, NP_006153, NP_765975, NP_765976, NP_765977, NP_765978

UniProt: O95644

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway