Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Laminin beta 1 anticorps (C-Term)

LAMB1 Reactivité: Souris WB, IHC (p) Hôte: Lapin Polyclonal RB33607 unconjugated
N° du produit ABIN657904
  • Antigène Voir toutes Laminin beta 1 (LAMB1) Anticorps
    Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
    Épitope
    • 9
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1691-1720, C-Term
    Reactivité
    • 49
    • 30
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 46
    • 5
    Lapin
    Clonalité
    • 38
    • 13
    Polyclonal
    Conjugué
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp Laminin beta 1 est non-conjugé
    Application
    • 30
    • 21
    • 18
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This LAMB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1691-1720 amino acids from the C-terminal region of human LAMB1.
    Clone
    RB33607
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LAMB1 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    LAMB1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Date de péremption
    6 months
  • Antigène
    Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
    Autre désignation
    LAMB1 (LAMB1 Produits)
    Synonymes
    anticorps CLM, anticorps LIS5, anticorps fc20b05, anticorps gup, anticorps lamb1, anticorps sb:cb95, anticorps wu:fc20b05, anticorps Lamb1-1, anticorps LAMB1, anticorps C77966, anticorps C80098, anticorps C81607, anticorps D130003D08Rik, anticorps Lamb-1, anticorps laminin subunit beta 1, anticorps laminin, beta 1a, anticorps laminin B1, anticorps LAMB1, anticorps lamb1a, anticorps Lamb1, anticorps lamb1
    Sujet
    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
    Poids moléculaire
    198038
    ID gène
    3912
    NCBI Accession
    NP_002282
    UniProt
    P07942
Vous êtes ici:
Support technique