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TIMP1 anticorps (AA 103-207)

TIMP1 Reactivité: Humain, Rat, Souris, Lapin WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN668331
  • Antigène Voir toutes TIMP1 Anticorps
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    Épitope
    • 18
    • 16
    • 15
    • 14
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 103-207
    Reactivité
    • 133
    • 72
    • 65
    • 23
    • 7
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Lapin
    Hôte
    • 122
    • 54
    • 6
    • 1
    • 1
    Lapin
    Clonalité
    • 124
    • 59
    Polyclonal
    Conjugué
    • 87
    • 25
    • 17
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Cet anticorp TIMP1 est non-conjugé
    Application
    • 138
    • 70
    • 58
    • 38
    • 25
    • 23
    • 22
    • 21
    • 19
    • 16
    • 10
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Lapin, Rat
    Homologie
    Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TIMP-1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Liang, Xiao, Long, Liu, Li, Liu, Yang: "Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy." dans: International journal of molecular medicine, Vol. 40, Issue 6, pp. 1781-1791, (2018) (PubMed).

    Varghese, Joseph, S R, B S, Sreelekha: "The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis." dans: International journal of biological macromolecules, Vol. 103, pp. 1000-1010, (2017) (PubMed).

    Sassoli, Chellini, Squecco, Tani, Idrizaj, Nosi, Giannelli, Zecchi-Orlandini: "Low intensity 635 nm diode laser irradiation inhibits fibroblast-myofibroblast transition reducing TRPC1 channel expression/activity: New perspectives for tissue fibrosis treatment." dans: Lasers in surgery and medicine, Vol. 48, Issue 3, pp. 318-32, (2016) (PubMed).

    Lu, Huang, Shih, Chang, Tsai, Lin, Shih: "Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0121077, (2015) (PubMed).

    Ni, Ding, Zhou, Qiu, Tang: "Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats." dans: European journal of pharmacology, Vol. 764, pp. 448-456, (2015) (PubMed).

    Watts, Bilska, Diab, Dunster, Bulmer, Barnett, Fraser: "Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injury." dans: Intensive care medicine experimental, Vol. 3, Issue 1, pp. 31, (2015) (PubMed).

    Sassoli, Nosi, Tani, Chellini, Mazzanti, Quercioli, Zecchi-Orlandini, Formigli: "Defining the role of mesenchymal stromal cells on the regulation of matrix metalloproteinases in skeletal muscle cells." dans: Experimental cell research, Vol. 323, Issue 2, pp. 297-313, (2014) (PubMed).

    Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: "The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage." dans: Cells, tissues, organs, Vol. 196, Issue 3, pp. 241-50, (2012) (PubMed).

    Jiang, Zhou, Liu: "Combined effects of the ATP-sensitive potassium channel opener pinacidil and simvastatin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension." dans: Die Pharmazie, Vol. 67, Issue 6, pp. 547-52, (2012) (PubMed).

  • Antigène
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    Autre désignation
    TIMP-1 (TIMP1 Produits)
    Synonymes
    anticorps TIMP-1, anticorps TIMP1, anticorps DKFZp468A0912, anticorps CLGI, anticorps EPA, anticorps EPO, anticorps HCI, anticorps TIMP, anticorps Timp, anticorps Clgi, anticorps TIMP metallopeptidase inhibitor 1, anticorps tissue inhibitor of metalloproteinase 1, anticorps TIMP1, anticorps Timp1
    Sujet

    Synonyms: EPA, EPO, HCI, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1

    Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP1, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro, but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

    ID gène
    7076
    UniProt
    P01033
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