C-JUN anticorps (AA 31-331)

N° du produit ABIN671691

Détail du produit anti-C-JUN anticorps

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Épitope: AA 31-331

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C-JUN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Poulet, Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human c-Jun

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-C-JUN (ABIN671691)

Liu, Lv, Ning, Yang, Zhu: "Therapeutic effects of 1,25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model." dans: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2284-2292, (2016) (PubMed).

Zhou, Lu, Wang, Xiao, Liu, Xing: "microRNA let-7c is essential for the anisomycin-elicited apoptosis in Jurkat T cells by linking JNK1/2 to AP-1/STAT1/STAT3 signaling." dans: Scientific reports, Vol. 6, pp. 24434, (2016) (PubMed).

Zhang, Lin, Jin, Lin, Cao, Zheng: "Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway." dans: Oncology reports, Vol. 36, Issue 1, pp. 23-30, (2016) (PubMed).

Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." dans: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).

Zhang, Pan, Xu, Niu, Ma, Xu: "Interleukin 18 augments growth ability via NF-?B and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells." dans: Gene, Vol. 563, Issue 1, pp. 45-51, (2015) (PubMed).

Détails sur C-JUN

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Autre désignation: c-Jun (JUN Produits)

Synonymes: anticorps AP-1, anticorps AP1, anticorps c-Jun, anticorps fj36h07, anticorps wu:fj36h07, anticorps zgc:65863, anticorps Junc, anticorps c-jun, anticorps CG2275, anticorps D-Jun, anticorps D-jun, anticorps D-jun/Jra, anticorps DJUN, anticorps DJun, anticorps Djun, anticorps Dmel\\CG2275, anticorps JRA, anticorps JUN, anticorps Jun, anticorps V, anticorps cJun, anticorps d-JRA, anticorps d-Jun, anticorps d-jun, anticorps dAP-1, anticorps dJRA, anticorps dJUN, anticorps dJra, anticorps dJun, anticorps djun, anticorps dm-Jun, anticorps jra, anticorps jun, anticorps l(2)46Ef, anticorps l(2)IA109, anticorps l(2R)IA109, anticorps Jun proto-oncogene, AP-1 transcription factor subunit, anticorps jun proto-oncogene S homeolog, anticorps jun proto-oncogene, anticorps Jun-related antigen, anticorps jun proto-oncogene L homeolog, anticorps JUN, anticorps Jun, anticorps jun.S, anticorps jun, anticorps Jra, anticorps jun.L

Sujet:

Synonyms: AP1, AP-1, c-Jun, Transcription factor AP-1, Activator protein 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

Background: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

ID gène: 3725

UniProt: P05412

Pathways: Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins