TRPM2 anticorps (AA 951-1050)

N° du produit ABIN681223

Détail du produit anti-TRPM2 anticorps

Antigène: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Épitope: AA 951-1050

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRPM2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TRPM2

Antigène: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Autre désignation: TRPM2 (TRPM2 Produits)

Synonymes: anticorps EREG1, anticorps KNP3, anticorps LTRPC2, anticorps NUDT9H, anticorps NUDT9L1, anticorps TRPC7, anticorps Trpm2-predicted, anticorps TRPM2, anticorps si:ch73-263b18.1, anticorps 9830168K16Rik, anticorps C79133, anticorps Trp7, anticorps Trrp7, anticorps transient receptor potential cation channel subfamily M member 2, anticorps transient receptor potential cation channel, subfamily M, member 2, anticorps transient receptor potential cation channel subfamily C member 7, anticorps TRPM2, anticorps Trpm2, anticorps trpm2, anticorps TRPC7

Sujet:

Synonyms: KNP3, EREG1, TRPC7, LTRPC2, NUDT9H, NUDT9L1, Transient receptor potential cation channel subfamily M member 2, Estrogen-responsive element-associated gene 1 protein, Long transient receptor potential channel 2, LTrpC-2, Transient receptor potential channel 7, TRPM2

Background: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

ID gène: 7226

UniProt: O94759