EPH Receptor A5 anticorps (EPHA5) (AA 468-500)

Details for Product anti-EPHA5 Antibody No. ABIN718661, Fournisseur: Connectez-vous pour afficher
Antigène
  • CEK7
  • EHK-1
  • EHK1
  • EK7
  • HEK7
  • TYRO4
  • AI854630
  • AW125296
  • Cek7
  • Ehk1
  • Els1
  • Hek7
  • Rek7
  • bsk
  • Els1.
  • EPHA5
  • EPH receptor A5
  • Eph receptor A5
  • EPHA5
  • epha5
  • Epha5
Épitope
AA 468-500
20
19
14
8
7
7
6
4
4
4
4
2
2
2
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
136
58
47
4
4
2
2
2
2
2
2
2
1
1
Hôte
Lapin
81
55
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp EPH Receptor A5 est non-conjugé
7
7
7
6
6
6
3
3
3
3
3
2
2
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
106
69
36
16
15
12
5
2
1
Options
Fournisseur
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Supplier Product No.
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic peptide derived from human EphA5/Eph receptor A5
Isotype IgG
Purification Purified by Protein A.
Autre désignation Eph Receptor A5 (EPHA5 Antibody Extrait)
Sujet

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).

Subcellular location: Extracellular

Synonyms: EK7, CEK7, EHK1, HEK7, EHK-1, TYRO4, Ephrin type-A receptor 5, Brain-specific kinase, EPH homology kinase 1, EPH-like kinase 7, EPHA5, BSK

ID gène 2044
UniProt P54756
Pathways Signalisation RTK
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-EPH Receptor A5 (EPHA5) (AA 468-500) antibody (ABIN718661) Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti EphA5/Eph ...
Immunofluorescence (IF) image for anti-EPH Receptor A5 (EPHA5) (AA 468-500) antibody (ABIN718661) Formalin-fixed and paraffin-embedded rat brain labeled with Anti-EphA5/Eph receptor A...
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