BMI1 anticorps
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- Antigène Voir toutes BMI1 Anticorps
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BMI1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- Nucleus
- Purification
- Protein G-Sepharose affinity purified
- Immunogène
- Synthetic peptide from the N-terminal region of human Bmi1, conjugated to KLH.
- Isotype
- IgG
- Top Product
- Discover our top product BMI1 Anticorps primaire
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- Indications d'application
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 50µg/50µl
- Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
- Autre désignation
- Bmi1 (BMI1 Produits)
- Synonymes
- anticorps FLVI2/BMI1, anticorps PCGF4, anticorps RNF51, anticorps AW546694, anticorps Bmi-1, anticorps Pcgf4, anticorps bmi1, anticorps pcgf4, anticorps psc1, anticorps wu:fb17g03, anticorps wu:fd18f06, anticorps BMI-1, anticorps pcgf4b, anticorps bmi-1, anticorps bmi1-a, anticorps bmi1-b, anticorps bmi1b, anticorps rnf51, anticorps xbmi-1, anticorps BMI1 proto-oncogene, polycomb ring finger, anticorps BMI1 polycomb ring finger oncogene, anticorps Bmi1 polycomb ring finger oncogene, anticorps bmi1 polycomb ring finger oncogene 1a, anticorps bmi1 polycomb ring finger oncogene 1b, anticorps BMI1 proto-oncogene, polycomb ring finger L homeolog, anticorps BMI1, anticorps LOC100230513, anticorps Bmi1, anticorps bmi1a, anticorps bmi1b, anticorps bmi1.L
- Sujet
- The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
- Poids moléculaire
- 37kDa
- NCBI Accession
- NM_005180
- Pathways
- Cycle Cellulaire, Autophagy
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