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BMI1 anticorps

BMI1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal unconjugated
N° du produit ABIN781173
  • Antigène Voir toutes BMI1 Anticorps
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Reactivité
    • 111
    • 47
    • 26
    • 11
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 77
    • 32
    • 6
    Souris
    Clonalité
    • 78
    • 37
    Monoclonal
    Conjugué
    • 78
    • 8
    • 8
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BMI1 est non-conjugé
    Application
    • 92
    • 49
    • 40
    • 21
    • 14
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificité
    Nucleus
    Purification
    Protein G-Sepharose affinity purified
    Immunogène
    Synthetic peptide from the N-terminal region of human Bmi1, conjugated to KLH.
    Isotype
    IgG
    Top Product
    Discover our top product BMI1 Anticorps primaire
  • Indications d'application
    Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    50µg/50µl
    Buffer
    0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Autre désignation
    Bmi1 (BMI1 Produits)
    Synonymes
    anticorps FLVI2/BMI1, anticorps PCGF4, anticorps RNF51, anticorps AW546694, anticorps Bmi-1, anticorps Pcgf4, anticorps bmi1, anticorps pcgf4, anticorps psc1, anticorps wu:fb17g03, anticorps wu:fd18f06, anticorps BMI-1, anticorps pcgf4b, anticorps bmi-1, anticorps bmi1-a, anticorps bmi1-b, anticorps bmi1b, anticorps rnf51, anticorps xbmi-1, anticorps BMI1 proto-oncogene, polycomb ring finger, anticorps BMI1 polycomb ring finger oncogene, anticorps Bmi1 polycomb ring finger oncogene, anticorps bmi1 polycomb ring finger oncogene 1a, anticorps bmi1 polycomb ring finger oncogene 1b, anticorps BMI1 proto-oncogene, polycomb ring finger L homeolog, anticorps BMI1, anticorps LOC100230513, anticorps Bmi1, anticorps bmi1a, anticorps bmi1b, anticorps bmi1.L
    Sujet
    The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
    Poids moléculaire
    37kDa
    NCBI Accession
    NM_005180
    Pathways
    Cycle Cellulaire, Autophagy
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