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CD19 anticorps (APC)

CD19 Reactivité: Humain FACS Hôte: Souris Monoclonal 4G7 APC
N° du produit ABIN781694
  • Antigène Voir toutes CD19 Anticorps
    CD19 (CD19 Molecule (CD19))
    Reactivité
    • 305
    • 180
    • 48
    • 30
    • 19
    • 10
    • 7
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    • 3
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    • 2
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    Humain
    Hôte
    • 185
    • 141
    • 63
    • 4
    Souris
    Clonalité
    • 261
    • 128
    • 2
    Monoclonal
    Conjugué
    • 118
    • 25
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    • 1
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    Cet anticorp CD19 est conjugé à/à la APC
    Application
    • 274
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    Flow Cytometry (FACS)
    Specificité
    This antibody recognizes CD19 (B4), a 95 kDa type I transmembrane glycoprotein of immunoglobulin superfamily, expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Immunogène
    Human CCL (chronic lymphocytic leukemia) cells
    Clone
    4G7
    Isotype
    IgG1
    Top Product
    Discover our top product CD19 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Stock
    4 °C
  • Antigène
    CD19 (CD19 Molecule (CD19))
    Autre désignation
    CD19 (CD19 Produits)
    Synonymes
    anticorps B4, anticorps CVID3, anticorps AW495831, anticorps CD19, anticorps CD19 molecule, anticorps CD19 antigen, anticorps CD19, anticorps Cd19
    Sujet
    CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
    ID gène
    930
    NCBI Accession
    NP_001761
    UniProt
    P15391
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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