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LY75/DEC-205 anticorps

LY75 Reactivité: Humain WB, FACS, IHC (fro) Hôte: Souris Monoclonal HD30 unconjugated
N° du produit ABIN781804
  • Antigène Voir toutes LY75/DEC-205 (LY75) Anticorps
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    Reactivité
    • 48
    • 38
    • 6
    • 5
    • 4
    • 2
    Humain
    Hôte
    • 40
    • 24
    • 12
    • 1
    • 1
    Souris
    Clonalité
    • 45
    • 32
    • 1
    Monoclonal
    Conjugué
    • 29
    • 9
    • 8
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp LY75/DEC-205 est non-conjugé
    Application
    • 29
    • 25
    • 22
    • 20
    • 14
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    This antibody recognizes CD205, an approx. 200 kDa C-type lectin transmembrane protein of the MMR (macrophage mannose receptor) family, expressed at high levels on dendritic cells and thymic epithelial cells, and at low levels on lymphocytes, NK cells and monocytes.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Protein-A affinity chromatography
    Pureté
    > 95 % pure (by SDS-PAGE)
    Immunogène
    Recombinant Fc-tagged human CD205
    Clone
    HD30
    Isotype
    IgG1
    Top Product
    Discover our top product LY75 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Antigène
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    Autre désignation
    CD205 / DEC-205 (LY75 Produits)
    Synonymes
    anticorps LY75, anticorps MGC140308, anticorps DEC205, anticorps im:7150926, anticorps si:dkey-78p20.2, anticorps LYT75, anticorps CD205, anticorps DEC-205, anticorps CLEC13B, anticorps GP200-MR6, anticorps LY-75, anticorps RGD1565962, anticorps Ly-75, anticorps lymphocyte antigen 75, anticorps CD205 protein, anticorps CD302 antigen, anticorps LY75, anticorps Cyan7822_2917, anticorps LY5, anticorps ly75, anticorps cd205, anticorps LOC100380704, anticorps LOC100433861, anticorps LOC100483541, anticorps Ly75
    Sujet
    CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6
    ID gène
    100526664
    NCBI Accession
    NP_001185688
    UniProt
    O60449
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