ZMYM2 anticorps (N-Term)

N° du produit ABIN783367

Détail du produit anti-ZMYM2 anticorps

Antigène: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZMYM2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ZMYM2 at N-term. At least two isoforms of ZMYM1 are known to exist, this antibody will detect only the shorter isoform. ZMYM1 antibody is predicted to not cross-react with other ZMYM protein family members.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the amino terminus of human ZMYM1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur ZMYM2

Antigène: ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))

Autre désignation: ZMYM2 (ZMYM2 Produits)

Synonymes: anticorps ZMYM2, anticorps ZNF198, anticorps fc07a10, anticorps wu:fc07a10, anticorps si:dkey-51d17.6, anticorps fim, anticorps mym, anticorps ramp, anticorps scll, anticorps zfp198, anticorps znf198, anticorps MGC83724, anticorps FIM, anticorps MYM, anticorps RAMP, anticorps SCLL, anticorps 5830413P05Rik, anticorps Zfp198, anticorps Znf198, anticorps zinc finger MYM-type containing 2, anticorps zinc finger, MYM-type 2, anticorps zinc finger MYM-type containing 2 L homeolog, anticorps ZMYM2, anticorps zmym2, anticorps zmym2.L, anticorps Zmym2

Sujet: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.Synonyms: FIM, Fused in myeloproliferative disorders protein, RAMP, Rearranged in atypical myeloproliferative disorder protein, ZNF198, Zinc finger MYM-type protein 2, Zinc finger protein 198

ID gène: 7750

NCBI Accession: NP_001177893

UniProt: Q9UBW7