Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ATP2C1 anticorps (C-Term)

ATP2C1 Reactivité: Humain, Souris WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN783438
  • Antigène Voir toutes ATP2C1 Anticorps
    ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
    Épitope
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    C-Term
    Reactivité
    • 40
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 35
    • 5
    Lapin
    Clonalité
    • 37
    • 3
    Polyclonal
    Conjugué
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ATP2C1 est non-conjugé
    Application
    • 27
    • 21
    • 7
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects ATP2C1 (C-term). At least four isoforms of ATP2C1 are known to exist, this antibody will recognize only the three longest isoforms. ATP2C1 antibody will not cross-react with ATP2C2.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    19 amino acid peptide near the carboxy terminus of human ATP2C1
    Top Product
    Discover our top product ATP2C1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
    Autre désignation
    ATP2C1 (ATP2C1 Produits)
    Synonymes
    anticorps ATP2C1, anticorps ATP2C1A, anticorps BCPM, anticorps HHD, anticorps PMR1, anticorps SPCA1, anticorps hSPCA1, anticorps Spca1, anticorps si:dkey-11p23.6, anticorps SPCA, anticorps 1700121J11Rik, anticorps AW061228, anticorps D930003G21Rik, anticorps pmr1, anticorps ATPase secretory pathway Ca2+ transporting 1, anticorps ATPase, Ca++ transporting, type 2C, member 1, anticorps ATPase, Ca++-sequestering, anticorps ATP2C1, anticorps atp2c1, anticorps Atp2c1
    Sujet
    ATP2C1, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1, belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder characterized by persistent blisters and erosions of the skin. Unlike the related protein ATP2C2, ATP2C1 is ubiquitously expressed and displays a lower maximal turnover rate for overall Ca2+-ATPase reaction and a higher apparent affinity for cytosolic Ca2+ activation of phosphorylation. Recent evidence suggests that ATP2C1 is a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers.Synonyms: ATP-dependent Calcium pump PMR1, ATPase 2C1, Calcium-transporting ATPase type 2C member 1, HUSSY-28, KIAA1347, PMR1L
    ID gène
    27032
    NCBI Accession
    NP_001001485
    UniProt
    P98194
    Pathways
    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
Vous êtes ici:
Support technique