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NALP8 anticorps (N-Term)

NLRP8 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN783713
  • Antigène Voir toutes NALP8 (NLRP8) Anticorps
    NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))
    Épitope
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    Humain
    Hôte
    • 2
    • 1
    Lapin
    Clonalité
    • 3
    Polyclonal
    Conjugué
    • 3
    Cet anticorp NALP8 est non-conjugé
    Application
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects NALP8 at N-term. This antibody is predicted to not cross-react with other NALP family members.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography purified via peptide column
    Immunogène
    16 amino acid peptide near the amino terminus of Human NALP8
    Top Product
    Discover our top product NLRP8 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))
    Autre désignation
    NALP8 (NLRP8 Produits)
    Synonymes
    anticorps CLR19.2, anticorps NALP8, anticorps NOD16, anticorps PAN4, anticorps NLR family pyrin domain containing 8, anticorps NLRP8
    Sujet
    NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.Synonyms: LRR and PYD domains-containing protein 8, NACHT, NLRP8, NOD16, PAN4, PYRIN and NACHT-containing protein 4
    ID gène
    126205
    NCBI Accession
    NP_789781
    UniProt
    Q86W28
    Pathways
    Inflammasome
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