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NLRP12 anticorps (N-Term)

NLRP12 Reactivité: Humain, Souris, Rat WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN783719
  • Antigène Voir toutes NLRP12 Anticorps
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    Épitope
    • 15
    • 8
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 51
    • 17
    • 15
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 49
    • 4
    • 1
    Lapin
    Clonalité
    • 50
    • 4
    Polyclonal
    Conjugué
    • 20
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NLRP12 est non-conjugé
    Application
    • 36
    • 33
    • 14
    • 13
    • 13
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects NALP2 at N-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    18 amino acid peptide near the amino terminus of human NALP12
    Top Product
    Discover our top product NLRP12 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Antigène
    NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
    Autre désignation
    NALP12 (NLRP12 Produits)
    Synonymes
    anticorps Nalp12, anticorps NALP12, anticorps CLR19.3, anticorps FCAS2, anticorps PAN6, anticorps PYPAF7, anticorps RNO, anticorps RNO2, anticorps NLR family, pyrin domain containing 12, anticorps NLR family pyrin domain containing 12, anticorps NACHT, LRR and PYD domains-containing protein 3, anticorps Nlrp12, anticorps NLRP12, anticorps LOC100018508
    Sujet
    NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.Synonyms: LRR and PYD domains-containing protein 12, Monarch-1, NACHT, NLRP12, PYPAF7, PYRIN-containing APAF1-like protein 7, RNO, Regulated by nitric oxide
    ID gène
    91662
    NCBI Accession
    NP_150639
    UniProt
    P59046
    Pathways
    Positive Regulation of Endopeptidase Activity, Inflammasome
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