SREBF2 anticorps (Middle Region)

N° du produit ABIN786556

Détail du produit anti-SREBF2 anticorps

Antigène: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Épitope: Middle Region

Reactivité: Humain, Rat, Chien, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SREBF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VMMGQEKVPI KQVPGGVKQL EPPKEGERRT THNIIEKRYR SSINDKIIEL

Réactivité croisée: Chien, Poulet, Humain, Souris, Porc, Lapin, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SREBF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SREBF2

Information d'application

Indications d'application: WB Suggested Anti-SREBF2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:7812500
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 681 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SREBF2

Antigène: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Autre désignation: SREBF2 / SREBP2 (SREBF2 Produits)

Synonymes: anticorps SREBF2, anticorps srebp2, anticorps SREBP2, anticorps zgc:158371, anticorps AI608257, anticorps SREBP-2, anticorps SREBP2gc, anticorps bHLHd2, anticorps lop13, anticorps nuc, anticorps Srebf2_retired, anticorps sterol regulatory element binding transcription factor 2, anticorps sterol regulatory element binding factor 2, anticorps sterol regulatory element binding transcription factor 2 L homeolog, anticorps SREBF2, anticorps srebf2, anticorps Srebf2, anticorps srebf2.L

Sujet: SREBF2 encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.
Alias Symbols: SREBP2, bHLHd2
Protein Interaction Partner: UBC, ERLIN2, MRPS6, NAE1, MAPK3, MAPK1, PARK7, SCAP, SREBF2, SREBF1, NPAT, HINFP, TRRAP, SUMO2, RNF139, SMAD3, HNF4A, ATF6, KLF13, LZTR1, ABLIM2, ATF7IP, ZDHHC17, COPS5, OS9, PIAS3, CASP8AP2, ARHGEF1, PIAS2, SLC4A4, PIAS1, ZYX, ZMYM2, UBE2I, TTC1, SPTBN1,
Protein Size: 681

Poids moléculaire: 74 kDa

ID gène: 6721

NCBI Accession: NM_004599

UniProt: Q12772

Pathways: Regulation of Lipid Metabolism by PPARalpha