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Doublecortin anticorps (AA 413-417)

DCX Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated

N° du produit ABIN871559

Fiche de données

Antigène Voir toutes Doublecortin (DCX) Anticorps

Doublecortin (DCX)
Épitope
7

7

7

7

5

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 413-417
Reactivité
110

73

67

4

3

3

2

2

2

1

1

1

1

1
Humain, Souris, Rat
Hôte
101

12

2

2
Lapin
Anticorps secondaires appropriés
Clonalité
97

20
Polyclonal
Conjugué
64

9

5

5

5

5

5

4

4

4

1

1

1

1

1

1

1
Cet anticorp Doublecortin est non-conjugé
Application
74

41

33

13

12

11

9

8

8

4

3

1

1

1

1
Western Blotting (WB)

Specificité

The antibody detects endogenous level of total Doublecortin protein.

Purification

Affinity purified

Immunogène

Peptide sequence around AA 413-417 ( P-T-S-P-G) derived from Human Doublecortin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

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Indications d'application

Western blotting: 1:500-1:1000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Antigène

Doublecortin (DCX)

Autre désignation

Doublecortin (DCX Produits)

Synonymes

anticorps DCX, anticorps DBCN, anticorps DC, anticorps LISX, anticorps SCLH, anticorps XLIS, anticorps Dbct, anticorps 18C15.5, anticorps doublecortin, anticorps DCX, anticorps Dcx

Sujet

Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.

Poids moléculaire

40-45 kDa

ID gène

1641

NCBI Accession

NP_000546

UniProt

O43602