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Caspase 3 anticorps (AA 29-33)

CASP3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN871646
  • Antigène Voir toutes Caspase 3 (CASP3) Anticorps
    Caspase 3 (CASP3)
    Épitope
    • 19
    • 16
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 11
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-33
    Reactivité
    • 282
    • 196
    • 149
    • 31
    • 17
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 282
    • 42
    • 4
    • 2
    • 2
    Lapin
    Clonalité
    • 274
    • 57
    Polyclonal
    Conjugué
    • 162
    • 27
    • 21
    • 14
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    Cet anticorp Caspase 3 est non-conjugé
    Application
    • 255
    • 109
    • 105
    • 85
    • 79
    • 65
    • 52
    • 37
    • 34
    • 29
    • 28
    • 20
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    The antibody detects endogenous level of total Caspase 3 protein.
    Purification
    Affinity purified
    Immunogène
    Peptide sequence around AA 29-33 (S-G-I-S-L) derived from Caspase 3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product CASP3 Anticorps primaire
  • Indications d'application
    Western blotting: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Shen, Song, An, Li, Wu, Ruan, Hu, Hu: "The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy." dans: Biomaterials, Vol. 35, Issue 1, pp. 316-26, (2013) (PubMed).

  • Antigène
    Caspase 3 (CASP3)
    Autre désignation
    Caspase 3 (CASP3 Produits)
    Synonymes
    anticorps CPP32, anticorps CPP32B, anticorps SCA-1, anticorps A830040C14Rik, anticorps AC-3, anticorps Apopain, anticorps CC3, anticorps Caspase-3, anticorps Lice, anticorps Yama, anticorps mldy, anticorps xcpp32, anticorps casp3, anticorps zgc:100890, anticorps CASP-3, anticorps caspase-3, anticorps caspase 3, anticorps caspase 3 S homeolog, anticorps caspase 3, apoptosis-related cysteine peptidase a, anticorps caspase 3, apoptosis-related cysteine peptidase, anticorps CASP3, anticorps Casp3, anticorps casp3.S, anticorps casp3a
    Sujet
    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
    Poids moléculaire
    17 kDa
    ID gène
    836
    NCBI Accession
    NP_004337
    UniProt
    P42574
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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