Nanog anticorps (AA 137-141)

N° du produit ABIN871649

Détail du produit anti-Nanog anticorps

Antigène: Nanog (NANOG) (Nanog Homeobox (NANOG))

Épitope: AA 137-141

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nanog est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous level of total Nanog protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 137-141 (K-Q-V-K-T) derived from Nano g Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Nanog

Antigène: Nanog (NANOG) (Nanog Homeobox (NANOG))

Autre désignation: Nanog (NANOG Produits)

Synonymes: anticorps 2410002E02Rik, anticorps ENK, anticorps ecat4, anticorps NANOG, anticorps hacp, anticorps wu:fd19e04, anticorps wu:fd20a07, anticorps zgc:193933, anticorps Nanog homeobox, anticorps nanog homeobox, anticorps Nanog, anticorps NANOG, anticorps nanog

Sujet: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed, promotes cells to enter into S phase and proliferation

Poids moléculaire: 42 kDa

ID gène: 79923

NCBI Accession: NP_079141

UniProt: Q9H9S0

Pathways: Stem Cell Maintenance