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Synaptophysin 2 anticorps (AA 257-261)

Reactivité: Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN871665
  • Antigène Tous les produits Synaptophysin 2
    Synaptophysin 2
    Épitope
    • 1
    • 1
    AA 257-261
    Reactivité
    • 9
    • 7
    • 7
    Rat
    Hôte
    • 9
    Lapin
    Clonalité
    • 9
    Polyclonal
    Conjugué
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Synaptophysin 2 est non-conjugé
    Application
    Western Blotting (WB)
    Specificité
    The antibody detects endogenous levels of total synaptophysin 2 protein.
    Purification
    Affinity purified
    Immunogène
    Peptide sequence around AA 257-261 (G-P-T-S-F) derived from Rat synaptophysin 2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
  • Indications d'application
    Western blotting: 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène
    Synaptophysin 2
    Abstract
    Synaptophysin 2 Produits
    Synonymes
    anticorps synaptoporin, anticorps Synpr
    Sujet
    Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex
    Poids moléculaire
    37 kDa
    ID gène
    66030
    NCBI Accession
    NP_076464
    UniProt
    P22831
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