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CIDEC anticorps (AA 101-200) (Alexa Fluor 488)

CIDEC Reactivité: Humain, Souris, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 488
N° du produit ABIN890706
  • Antigène Voir toutes CIDEC Anticorps
    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
    Épitope
    • 14
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 36
    • 5
    • 1
    Lapin
    Clonalité
    • 39
    • 3
    Polyclonal
    Conjugué
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CIDEC est conjugé à/à la Alexa Fluor 488
    Application
    • 39
    • 22
    • 12
    • 12
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Specificité
    Due to the similarity of this protein with CIDEA in Mouse and Rat, there is a chance that this antibody will react with this protein in those two species based on homology.
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CIDEC
    Isotype
    IgG
    Top Product
    Discover our top product CIDEC Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))
    Autre désignation
    CIDEC (CIDEC Produits)
    Synonymes
    anticorps fsp27, anticorps cide-3, anticorps MGC89274, anticorps cidec, anticorps MGC82483, anticorps CIDEC, anticorps fd36c01, anticorps wu:fd36c01, anticorps zgc:153033, anticorps CIDE-3, anticorps CIDE3, anticorps FPLD5, anticorps FSP27, anticorps Fsp27, anticorps CIDE-C, anticorps cell death inducing DFFA like effector c, anticorps cell death inducing DFFA like effector c S homeolog, anticorps cell death-inducing DFFA-like effector c, anticorps Cell death activator CIDE-3, anticorps cidec, anticorps cidec.S, anticorps CIDEC, anticorps Cidec
    Sujet

    Synonyms: CIDE3, FPLD5, FSP27, CIDE-3, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homolog, CIDEC

    Background: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

    ID gène
    63924
    UniProt
    Q96AQ7
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