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FAM3C anticorps (AA 151-227) (Alexa Fluor 350)

FAM3C Reactivité: Humain, Rat WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 350
N° du produit ABIN896534
  • Antigène Voir toutes FAM3C Anticorps
    FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
    Épitope
    • 14
    • 5
    • 3
    • 2
    • 2
    • 2
    AA 151-227
    Reactivité
    • 31
    • 19
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 28
    • 3
    Lapin
    Clonalité
    • 28
    • 3
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAM3C est conjugé à/à la Alexa Fluor 350
    Application
    • 26
    • 13
    • 12
    • 12
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Dog,Cow,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human FAM3C
    Isotype
    IgG
    Top Product
    Discover our top product FAM3C Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))
    Autre désignation
    FAM3C (FAM3C Produits)
    Synonymes
    anticorps ILEI, anticorps D6Wsu176e, anticorps Ilei, anticorps wu:fb99h11, anticorps wu:fi35h03, anticorps zgc:55444, anticorps zgc:77090, anticorps family with sequence similarity 3 member C, anticorps family with sequence similarity 3, member C, anticorps family with sequence similarity 3 member C L homeolog, anticorps fam3c, anticorps FAM3C, anticorps Fam3c, anticorps fam3c.L
    Sujet

    Synonyms: Fam3c, FAM3C_HUMAN, family with sequence similarity 3, member C, GS3786,ILEI, Interleukin-like EMT inducer, Predicted osteoblast protein, Protein FAM3C.

    Background: ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers.

    ID gène
    10447
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