DCAF6 anticorps (AA 245-350) (Alexa Fluor 647)

N° du produit ABIN908957

Détail du produit anti-DCAF6 anticorps (Alexa Fluor 647)

Antigène: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Épitope: AA 245-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCAF6 est conjugé à/à la Alexa Fluor 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NRIP

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DCAF6

Antigène: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Autre désignation: NRIP (DCAF6 Produits)

Synonymes: anticorps 1200006M05Rik, anticorps ARCAP, anticorps IQWD1, anticorps MSTP055, anticorps NRIP, anticorps PC326, anticorps Iqwd1, anticorps RGD1561961, anticorps DCAF6, anticorps si:rp71-20i5.1, anticorps arcap, anticorps dcaf6, anticorps iqwd1, anticorps mstp055, anticorps nrip, anticorps pc326, anticorps DDB1 and CUL4 associated factor 6, anticorps ddb1 and cul4 associated factor 6, anticorps DDB1 and CUL4 associated factor 6 S homeolog, anticorps DCAF6, anticorps Dcaf6, anticorps dcaf6, anticorps dcaf6.S

Sujet:

Synonyms: Androgen receptor complex associated protein, ARCAP, IQ mot and WD repeats 1, IQWD1v MSTP055, Nuclear receptor interaction protein, RP4 745I14.1, DCAF6_HUMAN.

Background: WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

ID gène: 8204