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TUSC2 anticorps (AA 31-100) (Alexa Fluor 555)

TUSC2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 555
N° du produit ABIN919019
  • Antigène Voir toutes TUSC2 Anticorps
    TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
    Épitope
    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-100
    Reactivité
    • 29
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 2
    • 1
    Lapin
    Clonalité
    • 29
    • 1
    Polyclonal
    Conjugué
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TUSC2 est conjugé à/à la Alexa Fluor 555
    Application
    • 27
    • 15
    • 12
    • 12
    • 9
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human TUSC2
    Isotype
    IgG
    Top Product
    Discover our top product TUSC2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TUSC2 (Tumor Suppressor Candidate 2 (TUSC2))
    Autre désignation
    TUSC2 (TUSC2 Produits)
    Synonymes
    anticorps C3orf11, anticorps FUS1, anticorps PAP, anticorps PDAP2, anticorps TUSC2, anticorps 1190001E22Rik, anticorps AA407686, anticorps Fus1, anticorps Lgcc, anticorps Pdap2, anticorps zgc:92701, anticorps zgc:153746, anticorps tumor suppressor candidate 2, anticorps tumor suppressor candidate 2 L homeolog, anticorps tumor suppressor candidate 2b, anticorps tumor suppressor candidate 2a, anticorps TUSC2, anticorps tusc2.L, anticorps Tusc2, anticorps tusc2b, anticorps tusc2a
    Sujet

    Synonyms: C3orf11, FUS1, Fusion 1 protein, PAP, PDAP2, PDGFA associated protein 2, Tumor suppressor candidate 2, TUSC 2, TUSC2_HUMAN.

    Background: TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.

    ID gène
    11334
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