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CD19 anticorps (FITC)

CD19 Reactivité: Humain FACS Hôte: Souris Monoclonal LT19 FITC
N° du produit ABIN94015
  • Antigène Voir toutes CD19 Anticorps
    CD19 (CD19 Molecule (CD19))
    Reactivité
    • 305
    • 180
    • 48
    • 30
    • 19
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 185
    • 141
    • 63
    • 4
    Souris
    Clonalité
    • 261
    • 128
    • 2
    Monoclonal
    Conjugué
    • 118
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
    • 1
    • 1
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    • 1
    Cet anticorp CD19 est conjugé à/à la FITC
    Application
    • 274
    • 121
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    • 1
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    Flow Cytometry (FACS)
    Specificité
    The antibody LT19 reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    Daudi human Burkitt lymphoma cell line
    Clone
    LT19
    Isotype
    IgG1
    Top Product
    Discover our top product CD19 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Reconstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Avoid prolonged exposure to light.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Kayserova, Vcelakova, Stechova, Dudkova, Hromadkova, Sumnik, Kolouskova, Spisek, Sediva: "Decreased dendritic cell numbers but increased TLR9-mediated interferon-alpha production in first degree relatives of type 1 diabetes patients." dans: Clinical immunology (Orlando, Fla.), Vol. 153, Issue 1, pp. 49-55, (2014) (PubMed).

    Elias, Flo, Lopez, Zorzopulos, Montaner, Rodriguez: "Strong cytosine-guanosine-independent immunostimulation in humans and other primates by synthetic oligodeoxynucleotides with PyNTTTTGT motifs." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3697-704, (2003) (PubMed).

  • Antigène
    CD19 (CD19 Molecule (CD19))
    Autre désignation
    CD19 (CD19 Produits)
    Synonymes
    anticorps B4, anticorps CVID3, anticorps AW495831, anticorps CD19, anticorps CD19 molecule, anticorps CD19 antigen, anticorps CD19, anticorps Cd19
    Sujet
    CD19 Molecule,CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.,B4, Leu-12, CVID3
    ID gène
    930
    UniProt
    P15391
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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