CYP1A1 anticorps (AA 1-512)

N° du produit ABIN947763

Détail du produit anti-CYP1A1 anticorps

Antigène: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Épitope: AA 1-512

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP1A1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Mouse polyclonal antibody raised against a full-length human CYP1A1 protein.

Séquence: MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: CYP1A1 (NP_000490.1, 1 a.a. ~ 512 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CYP1A1 (ABIN947763)

Zapletal, Tylichová, Neča, Kohoutek, Machala, Milcová, Pokorná, Topinka, Moyer, Hofmanová, Kozubík, Vondráček: "Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models." dans: Archives of toxicology, Vol. 91, Issue 5, pp. 2135-2150, (2016) (PubMed).

Kabátková, Zapletal, Tylichová, Ne?a, Machala, Milcová, Topinka, Kozubík, Vondrá?ek: "Inhibition of ?-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation." dans: Mutagenesis, Vol. 30, Issue 4, pp. 565-76, (2015) (PubMed).

Détails sur CYP1A1

Antigène: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Autre désignation: CYP1A1 (CYP1A1 Produits)

Sujet: Full Gene Name: cytochrome P450, family 1, subfamily A, polypeptide 1
Synonyms: AHH,AHRR,CP11,CYP1,P1-450,P450-C,P450DX

ID gène: 1543

NCBI Accession: NM_000499

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha