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Androgen Receptor anticorps (Middle Region)

AR Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN950408
  • Antigène Voir toutes Androgen Receptor (AR) Anticorps
    Androgen Receptor (AR)
    Épitope
    • 21
    • 20
    • 19
    • 18
    • 17
    • 17
    • 15
    • 13
    • 13
    • 12
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-309, Middle Region
    Reactivité
    • 304
    • 93
    • 89
    • 29
    • 19
    • 17
    • 15
    • 12
    • 8
    • 4
    • 4
    • 3
    • 1
    Humain
    Hôte
    • 255
    • 52
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 245
    • 63
    Polyclonal
    Conjugué
    • 117
    • 27
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Androgen Receptor est non-conjugé
    Application
    • 179
    • 89
    • 65
    • 58
    • 53
    • 40
    • 33
    • 22
    • 19
    • 17
    • 16
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to Androgen receptor.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogène
    KLH conjugated synthetic peptide between 281-309 amino acids from the Central region of human AR
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AR Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) sodium azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Androgen Receptor (AR)
    Autre désignation
    Androgen Receptor (AR Produits)
    Synonymes
    anticorps AIS, anticorps DHTR, anticorps HUMARA, anticorps HYSP1, anticorps KD, anticorps NR3C4, anticorps SBMA, anticorps SMAX1, anticorps TFM, anticorps AW320017, anticorps Tfm, anticorps Andr, anticorps AR, anticorps androgen receptor, anticorps AR, anticorps Ar, anticorps ar
    Sujet
    The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq].Synonyms: DHTR, Dihydrotestosterone receptor, NR3C4, Nuclear receptor subfamily 3 group C member 4
    ID gène
    367
    NCBI Accession
    NP_000035
    Pathways
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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