BAG4 anticorps (C-Term)

N° du produit ABIN950598

Détail du produit anti-BAG4 anticorps

Antigène: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Épitope: AA 380-409, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to BAG4.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 380-409 amino acids from the C-terminal region of human BAG4

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BAG4

Antigène: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Autre désignation: BAG4 (BAG4 Produits)

Synonymes: anticorps BAG-4, anticorps SODD, anticorps BAG4, anticorps fd20a04, anticorps wu:fd20a04, anticorps si:dkey-220o5.3, anticorps 2410112I15Rik, anticorps ATBAG4, anticorps BCL-2-associated athanogene 4, anticorps BCL2 associated athanogene 4, anticorps BCL2-associated athanogene 4, anticorps BCL-2-associated athanogene 4, anticorps BAG4, anticorps Bag4, anticorps bag4

Sujet: BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.Synonyms: BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, SODD, Silencer of death domains

ID gène: 9530

NCBI Accession: NP_004865

Pathways: Regulation of Actin Filament Polymerization