SLAMF1 anticorps

N° du produit ABIN951192

Détail du produit anti-SLAMF1 anticorps

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SLAMF1 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Specificité: This Monoclonal SLAM.4 antibody recognizes CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein A-affinity chromatography

Immunogène: Human CD150-transfected 300.19 cells

Clone: SLAM-4

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL (> 95% pure by SDS-PAGE)

Buffer: Azide free phosphate buffered saline (PBS), pH ~7.4, 0.2 μm filter sterilized

Agent conservateur: Azide free

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur SLAMF1

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Autre désignation: CD150 / SLAMF1 (SLAMF1 Produits)

Synonymes: anticorps CD150, anticorps SLAM, anticorps SLAMF1, anticorps 4933415F16, anticorps AA177906, anticorps CDw150, anticorps ESTM51, anticorps IPO-3, anticorps Slam, anticorps RGD1560634, anticorps signaling lymphocytic activation molecule family member 1, anticorps SLAMF1, anticorps Slamf1

Sujet: CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam

ID gène: 6504

NCBI Accession: NP_003028

UniProt: Q13291